S04-01 Calfacilitin: A new player in neural induction

نویسندگان

  • Costis Papanayotou
  • Ping Liao
  • Song-Quing Lu
  • Lei Zhu
  • Alex Shaw
  • Andrea Streit
  • Dejie Yu
  • Tuck Wah Soong
  • Claudio D. Stern
  • Guojun Sheng
چکیده

S04-01 Calfacilitin: A new player in neural induction Costis Papanayotou, Ping Liao, Song-Quing Lu, Lei Zhu, Alex Shaw, Andrea Streit, Dejie Yu, Tuck Wah Soong, Claudio D. Stern, Guojun Sheng University College London, London, United Kingdom National University of Singapore, Singapore, Singapore National Neuroscience Institute, Singapore, Singapore King’s College London, London, United Kingdom Institut Jacques-Monod, Paris, France Origen Theraputics, CA, United States RIKEN Center for Developmental Biology, Kobe, Japan

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Calcium fluxes have been implicated in the specification of the vertebrate embryonic nervous system for some time, but how these fluxes are regulated and how they relate to the rest of the neural induction cascade is unknown. Here we describe Calfacilitin, a transmembrane calcium channel facilitator that increases calcium flux by generating a larger window current and slowing inactivation of th...

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عنوان ژورنال:
  • Mechanisms of Development

دوره 126  شماره 

صفحات  -

تاریخ انتشار 2009